If you decide to pledge final loyalty with the institute faction in fallout 4 then you will no longer be able to complete quests or contact allies of other factions.
Fallout 4 siding with the institute ending.
There are no rewards to speak of for siding with any of the factions.
The main story concludes once you reach the institute.
Fallout 4 destroying the brotherhood siding with the institute aftermath mercenary mulluns.
The institute s experiments with the forced evolutionary virus or fev ended when doctor virgil went rogue and fled into the commonwealth.
But with the institute ending you become director and even if it isnt explicitely stated in the game you can imagine manufacturing things like the g e c k and sending synths to clean up the planet.
After that point you re given the choice of either helping one of the main four factions.
In this ending the brotherhood of steel destroys the railroad and the institute and the sole survivor is promoted to the position of sentinel.
You will need to complete a.
But even with the organic synth project complete the institute did not rest on its laurels.
Disappointment at institute end game spoilers last night i reached the endof fallout 4 siding with the institute i destroyed both the brotherhood of steel and the railroad and pretty much had little to no lasting effect on my relationship with the minutemen.
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The only differences are who you can do quests for after the end clip.
All four factions will have been met by that time they are the brotherhood the minutemen the railroad and the institute.
Why the institute ending is good for the commonwealth pumatheories duration.
To simplify it as much as possible you are always allied with the minutemen but when it comes to the other 3 whichever one you choose will be the only one you can continue to be allies with afterwards.
Even though their missions have been accomplished the brotherhood does not leave the commonwealth and continue with their other tasks.
Work continues in other fields its sophistication increasing with every day.